During a White House briefing on autism research, President Donald Trump struggled to pronounce “acetaminophen,” the active ingredient in Tylenol.
In a brief, awkward moment, Trump said, “Ah-ced-uv… well, let’s see how we say that. Ascenem – enophin. Acetaminophen. Is that ok?”
The slip prompted laughter from attendees and quickly went viral across social media platforms, including X, TikTok, and Instagram.
Trump: "Asceda -- well, let's see how we say that. Ascenem -- enophin. Acetaminophen. Is that okay?" pic.twitter.com/EVp7IGSksk
— Aaron Rupar (@atrupar) September 22, 2025
The pronunciation gaffe has drawn widespread attention, with hashtags like #TrumpPronunciation and #Acetaminophen trending online. Clips of the incident have already amassed millions of views, with commentators highlighting the moment as an unusual and humorous lapse during an official briefing.
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Late-night host Jimmy Kimmel addressed the incident, quipping, “Even the drug’s name is too complicated for him.”
While the briefing itself focused on controversial claims linking prenatal acetaminophen use to autism and ADHD, it was the mispronunciation that dominated public discussion.
Media outlets and commentators noted that the pronunciation slip overshadowed the briefing’s intended message.
Experts and medical professionals have clarified that the primary discussion about acetaminophen and autism is separate from the viral moment.
Nevertheless, the mispronunciation has become the most talked-about aspect of the briefing, demonstrating how even small verbal missteps can capture massive public attention.
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