The attackers, riding a motorbike, threw a hand grenade at a car which on explosion injured the passengers. The car was also badly damaged in the blast.
A heavy police contingent reached the crime scene including DIG Naeem Akram Borkha who inspected the area.
The injured were identified as Salman Baloch and Rizwan and are said to be affiliated with the Pakistan Peoples Party.
According to Express News correspondent Nadeem Ahmed, the injured were shifted to a local hospital and are in a serious condition.
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@Mohammad Ali Siddiqui: wow, you believe in the DIG! Btw, can anyone in Gulberg (Karachi - Central) say something that irks 'bhai'?
it wasn't hand grenade attack, DIG West says explosive was inside Dash board of PPP leader's car