The series, based on Indian author Vikram Chandra's novel of the same name, will feature Saif as Sartaj Singh.
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"Content in the digital space is taking over the existing dynamics at a rapid pace - the crown in the digital empire lies with Netflix, and it's extremely satisfying to partner and participate in the first original series from India to be showcased on Netflix," Saif said in a statement.
Set in Mumbai, the series delves into the city's intricate web of organised crime, corruption, politics and espionage that lie beneath India's economic renaissance. It is an epic masterwork of exceptional richness and power that interweaves the lives of the privileged, the famous, the wretched and the bloodthirsty.
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"Saif Ali Khan is a true pioneer and risk-taker in Indian cinema, and we could not be more delighted to be working with him on ‘Sacred Games'," said Erik Barmack, Vice President of international original series at Netflix.
"His role is layered and complex, and we are thrilled to be working with such a fantastic actor to bring this story to a global audience," Barmack added.
Shot in India, the series will be produced in partnership with Phantom Films.
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