"A vehicle close to a militant compound was the target of the strike in the Shonkrai Narai village of South Waziristan," an official said.
The official confirmed the death toll; however, did not delve into details regarding identities of the deceased.
Read: Drone strike in North Waziristan kills five suspected militants
Further, sources said the area has heavy presence of Sajna group of the Taliban faction.
The drone strike comes after a long halt, as North Waziristan has been the main target of drone strikes in recent months. At least five suspected militants were killed when a US drone fired two missiles at a compound in North Waziristan, officials said on September 1.
Read: Pakistan condemns North Waziristan drone strike
Earlier this week, security forces imposed a curfew in South Waziristan after a convoy came under attack which left one dead and injuring five security personnel.
Meanwhile, the army continues its Operation in the nearby Shawal Valley where a ground offensive was launched last month.
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