Eating citrus fruits may increase risk of skin cancer

Higher overall citrus fruit consumption was associated with increased risk of malignant melanoma in both men and women

Ians July 06, 2015
Higher overall citrus fruit consumption was associated with increased risk of malignant melanoma in both men and women. PHOTO: ALEXANDERMKT

Frequent consumption of citrus fruits - whole grapefruit and orange juice - may be associated with an increased risk of melanoma, a type of skin cancer, says a large study.

Analysing dietary patterns among more than 100,000 people in the US, the researchers found that melanoma risk was 36 per cent higher in people who consumed citrus fruit or juice at least 1.6 times daily compared to those who consumed them less than twice per week.

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Consumption of grapefruit and oranges was not associated with an increased risk for any other non-skin cancers.

"While our findings suggest that people who consume large amounts of whole grapefruit or orange juice may be at increased risk for melanoma, we need much more research before any concrete recommendations can be made," said lead study author Shaowei Wu, postdoctoral research fellow at Brown University in Providence, Rhode Island.

"At this time, we do not advise that people cut back on citrus - but those who consume a lot of grapefruit and/or orange juice should be particularly careful to avoid prolonged sun exposure," Wu noted.


The apparent link between melanoma and citrus fruit consumption may be due to high levels of substances called furocoumarins found in citrus fruits, the researchers pointed out.

Prior research showed that furocoumarins make the skin more sensitive to sunlight, including to melanoma-causing ultraviolet (UV) rays.

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The new study involved over 100,000 men and women in the US. Over a follow-up period of up to 26 years, 1,840 study participants were diagnosed with melanoma.

Higher overall citrus fruit consumption (the total number of servings of whole grapefruit, whole oranges, and juices from those fruits) was associated with increased risk of malignant melanoma in both men and women.

The association was strongest for grapefruit, followed by orange juice.


AA | 8 years ago | Reply The research is inconclusive because there is no method of research that can confirm the relationship, whether the people consumed citrus juice consistently all their life the way they claim or at the time of research. Simple questions such as How many times you drink citrus juice daily does not capture the consistency. Cancer research is also grossly inconclusive because its done on cases already diagnosed. There could be millions who had been consuming citrus juices and never developed Melanoma and never been asked. So please be very cautious on changing your dietary habits based on such researches until much extensive research about the claimed relationship is proved to cause melanoma in animal research just by consuming the furocoumarins. Even then it is still questionable since many fruits contain one chemical also contains neutralizers.
Yahya Farooq | 8 years ago | Reply Such studies only make me cut back on articles.
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