Four victims were inside the shop whereas the other two victims were passersby, police sources said.
A heavy contingent of police reached the crime scene and cordoned off the area. A search operation is underway.
Bodies of the victims were shifted to Civil Hospital where relatives of the deceased staged protests.
Police sources said that this appeared to be an incident of target killing.
Earlier, two Balochistan Levies personnel were killed in an attack on a check post, and a Hazara community member was shot dead, in separate incidents of violence.
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More blood spilled - it's anyway cheaper than water now..
@Ali Mardan: This time people of that ethnicity were targeted which are in majority in Punjab so we did not see any condemnation actually by any party of Balochistan. For some people hatred against one Ethnicity of Punjab is so immense that according to them victims will be in Hell rather than in Heaven after they will be murdered.
An other family lost his bread earners and innocent children are made orphan. Some devils might have secured "booked" his place in heaven by taking innocent lives. All my condolances to the family members of those who lost their lives and embraced Shahaddat.