Mayweather, who improved to 48-0 by beating Pacquiao in May, missed a deadline by which he had to pay a $200,000 sanctioning fee from the fight and vacate the junior middleweight title he also held, the WBO said in a statement.
Read: Boxing: Mayweather beats Pacquiao in 'Fight of the Century' by decision
The WBO said it is against rules for boxers to hold world titles in multiple weight classes and that Mayweather had to indicate which weight division he he would retain.
According to @WorldBoxingOrg Floyd has not complied with the rules by today's 4:30 pm ET deadline. Likely to be stripped of 147 on Monday.
— Dan Rafael (@DanRafael1) July 3, 2015
Mayweather, who finished ahead on all three scorecards of what proved to be the top-grossing prize fight of all-time, had until 4:30 p.m. ET (2030 GMT) last Friday to advise the WBO of his position.
https://instagram.com/p/4llTgdR3Vw/?taken-by=floydmayweather
"The WBO World Championship Committee is allowed no other alternative but to cease to recognize Mr. Floyd Mayweather, Jr. as the WBO Welterweight Champion of the World and vacate his title, for failing to comply with our WBO Regulations of World Championship Contests," the WBO said in a statement.
Read: Mayweather considers rematch as fight fans sue Pacquiao
Mayweather, who earned over $200 million from the fight which generated a record pay-per-view revenue in the United States of $400 million, has two weeks to launch an appeal.
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