"The four Shiites had just closed their shop and left for home when an unknown gunman opened fire on their car and ran away," killing two people on the spot, senior local police official Hamid Shakeel told AFP.
He said the other two people died of their injuries on the way to hospital.
No one had claimed responsibility for the attack, Shakeel added. A second police official, Shaukat Ali, confirmed the incident.
Meanwhile, heavy contingents of police cordoned off the area and started investigations.
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