Nancy Guthrie case update: Sheriff says new DNA evidence could lead to major breakthrough

Investigators believe new DNA evidence could be the key to solving the disappearance of Nancy Guthrie, the 84-year-old mother of Today co-anchor Savannah Guthrie.

In a recent update, Pima County Sheriff Chris Nanos said advances in DNA testing may provide the major breakthrough authorities have been waiting for more than 100 days after Nancy vanished from her Tucson home.

“We may have some breakthroughs with the DNA,” Nanos said, expressing cautious optimism while stressing that investigators are being careful not to rush to conclusions.

Nancy Guthrie disappeared on February 1, 2026, after a masked intruder was captured on surveillance footage outside her home. Authorities believe she was abducted, and the case has been investigated as a likely homicide, though her body has not been found.

Sheriff Nanos said law enforcement is continuing to analyse both biological and digital evidence, including surveillance footage and tips submitted to the FBI and local authorities. He emphasised that investigators are committed to building a strong case before making any arrests.

The Guthrie family has offered a $1 million reward for information leading to Nancy’s safe return, while the FBI is also offering a separate reward for information that leads to an arrest and conviction.

Savannah Guthrie has remained vocal about the search for her mother, using social media and national television appearances to urge anyone with information to come forward.

Although no suspect has been publicly identified, Nanos said investigators believe they are getting closer to answers and remain determined to solve the case.