Bodies littered the scene and a towering plume of smoke rose from the area, which houses foreign embassies, after the blast blew out the windows in several missions and residences hundreds of metres away.
Witnesses described dozens of cars choking the roads as wounded survivors and panicked schoolgirls sought safety, with men and women struggling to get through security checkpoints to search for loved ones.
Powerful blast targets NATO convoy in Kabul
It was not immediately clear what the target was. But the attack underscores spiralling insecurity in Afghanistan, where a military beset by soaring casualties and desertions is struggling to beat back the insurgents. Over a third of the country is outside government control.
More than an hour after the explosion, ambulances were still taking the wounded to hospital as firefighters struggled to control blazes in several buildings. Health ministry spokesperson Waheed Majroh said at least 49 people had been killed and 320 wounded, with the figures confirmed by a second health official and the government media office.
Authorities warned the toll could yet rise. "They are still bringing bodies and wounded people to hospitals," senior health ministry spokesperson Ismael Kawoosi told AFP. The interior ministry was calling on Kabul residents to donate blood, saying hospitals were in "dire need".
Men move an injured man to a hospital after a blast in Kabul, Afghanistan May 31, 2017. PHOTO: REUTERS
There was no immediate claim of responsibility, but the attack came as the resurgent Taliban step up their annual "spring offensive".
The Islamic State group has also claimed responsibility for several recent bombings in the Afghan capital, including a powerful blast targeting an armoured NATO convoy that killed at least eight people and wounded 28 on May 3.
Najib Danish, an interior ministry spokesperson, said initial findings showed it had been a truck bomb.
Pakistani diplomats sustain minor injuries, residences damaged: FO
The blast also inflicted minor injuries to the staffers of Pakistani embassy situated in Kabul and damaged the residences of country’s diplomats posted in Afghanistan, Foreign Office said following the attack.
The office also condemned the deadly blast and said Pakistan a victim of terrorism understand the agony that Afghanistan must be going through.
An FO statement said that Pakistan firmly stands with Afghan people in time of grief.
Army chief condemns Kabul blast
Army chief General Qamar Javed Bajwa has condemned the blast in Kabul, Inter-Services Public Relations said on Wednesday.
According to the military’s media wing, Gen Bajwa expressed grief on loss of precious lives and damage to various embassies’ infrastructure including Pakistan. “We stand with Afghan brothers and its security forces in fight against terrorism and militancy.”
Manpreet Vohra, India's envoy to Afghanistan, told the Times Now television channel the bomb went off around 100 metres from India's embassy, one of several in the area.
At least one dead, 35 wounded in Kabul attacks
"We are all safe, all our staff, all our personnel are safe. However, the blast was very large and nearby buildings including our own building have considerable damage in terms of broken glass and shattered windows and blown doors etc," he said.
Indian Prime Minister Narendra Modi tweeted: "We strongly condemn the terrorist blast in Kabul. Our thoughts are with the families of the deceased & prayers with the injured."
We strongly condemn the terrorist blast in Kabul. Our thoughts are with the families of the deceased & prayers with the injured.
— Narendra Modi (@narendramodi) May 31, 2017
India stands with Afghanistan in fighting all types of terrorism. Forces supporting terrorism need to be defeated.
— Narendra Modi (@narendramodi) May 31, 2017
"By God's grace, Indian Embassy staff are safe in the massive #Kabul blast," India's foreign minister Sushma Swaraj tweeted. The Indian embassy is among those close to the area.
By God's grace, Indian Embassy staff are safe in the massive #Kabul blast.
— Sushma Swaraj (@SushmaSwaraj) May 31, 2017
The explosion also shattered windows at the Japanese embassy. "Two Japanese embassy staffers were mildly injured, suffering cuts," a foreign ministry official in Tokyo told AFP. France also reported damage to its own embassy and the German one.
Afghan security personnel are seen at the site of a car bomb attack in Kabul on May 31, 2017. PHOTO: AFP
French embassy in Kabul damaged in car bomb attack: minister
The French embassy in Kabul was damaged in Wednesday's car bomb attack in the Afghanistan capital, said French minister Marielle de Sarnez, who added there were no signs at this stage of any French victims. "There has been some material damage in the French embassy, as well as in the Germany embassy," de Sarnez, who is France's European affairs minister, told Europe 1 radio on Wednesday.
A driver associated with the BBC was among those killed and four other journalists were wounded in the blast, the news organisation said in a statement.
BBC statement: pic.twitter.com/FBl4IRi16E
— BBC News Press Team (@BBCNewsPR) May 31, 2017
Pentagon chief Jim Mattis has warned of "another tough year" for both foreign troops and local forces in Afghanistan.
At least three killed in Kabul suicide attack near Afghan Defence Ministry
Afghan troops are backed by US and NATO forces, and the Pentagon has reportedly asked the White House to send thousands more troops to the country to break the deadlock in the fight against the Taliban.
US troops in Afghanistan number about 8,400 today, and there are another 5,000 from NATO allies. They mainly serve in an advisory capacity -- a far cry from the US presence of more than 100,000 six years ago.
The blast was the latest in a long line of attacks in Kabul. The province surrounding the capital had the highest number of casualties in the first three months of 2017 due to multiple attacks in the city, with civilians bearing the brunt of the violence.
[brid video="143296" player="7247" title="Massive Kabul truck bomb kills 90 wounds hundreds"]
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