Two of the bombers detonated their vehicle-borne explosives at the western gate of Camp Speicher, a former US base outside the city of Tikrit.
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Three others exploded themselves after entering the section of the base where Iraqi police are being trained, police and military sources in the Salahuddin operations command said.
Islamic State, the militant group controlling swathes of Iraq's north and west, claimed responsibility for the blasts in a statement distributed by supporters online.
It said it targeted "trainers from the rejectionist army", a term used by the Sunni insurgents to describe Shia Muslims.
Iraq is gripped by a sectarian conflict mostly between Shia and Sunnis that has been exacerbated by the rise of the ultra-hardline Sunni insurgents of Islamic State.
Camp Speicher became a symbol of the group's brutality and hatred for Iraq's Shia majority after as many as 1,700 soldiers from the base were killed in mid-2014 during the militants' lightning advance across the Syrian border.
Iraq PM vows to defeat Islamic State in 2016 after army's first major victory
Iraqi forces retook the center of the western city of Ramadi last week, a victory that could help boost Prime Minister Haider al-Abadi, who has been rebuilding the military after stunning defeats in the face of Islamic State.
Iraq's Defense Ministry said Islamic State has stepped up suicide blasts in response to setbacks in Ramadi. It said in a statement the group had used 22 bombers in two recent failed attacks in Anbar where Ramadi is located. The military responded, killing at least 42 militants including the bombers, the ministry said.
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