Zardari had spoken to former US ambassador Anne Patterson in 2009, saying that he had instructed his son Bilawal Bhutto Zardari to name his sister Faryal Talpur as President if he is assassinated, reported The Guardian.
In another cable quoted by the newspaper, US Vice President Joe Biden recounted to Britain's then Prime Minister Gordon Brown a conversation with Zardari last year. Zardari told him that Kayani and the Inter-Services Intelligence agency "will take me out," according to the cable.
Another memo cited in The New York Times quotes General Ashfaq Kayani, chief of the military, telling the US ambassador during a March 2009 meeting that he "might, however reluctantly," pressure Zardari to resign.
Kayani was quoted as saying that he might support Asfandyar Wali Khan, leader of the Awami National League Party, as the new president -- not Zardari's arch-nemesis Nawaz Sharif.
The cables also laid bare US frustrations at what officials see as Pakistan's refusal to cut off ties with extremists such as Lashkar-e-Taiba, which is blamed for carrying out the bloody 2008 siege of Mumbai.
"There is no chance that Pakistan will view enhanced assistance levels in any field as sufficient compensation for abandoning support for these groups, which it sees as an important part of its national security apparatus against India," Ambassador Anne Patterson said in a cable quoted by the Times.
The cables also touch on allegations of extrajudicial killings by Pakistani forces, according to the Times.
A cable last year suggested there was credible evidence that the or paramilitary forces killed some detainees after an offensive against Taliban insurgents in the northwestern regions.
The embassy said that news of killings should not be leaked to the press, for fear of offending the Pakistani army. However, this year the United States said it would cut off support for some Pakistani units following the release of a video that appeared to show extrajudicial killings.
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