The strike was carried out on Wednesday on a training camp in the eastern province of Khost near the Pakistan-Afghanistan border, local authorities said.
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They said it was launched by the United States. There was no immediate confirmation from the US-dominated Nato force which is combating Taliban and other militants in Afghanistan.
It is unclear how many people were killed. The Khost provincial governor put the figure as high as 50 but that could not be confirmed.
A Pakistani security official and residents told AFP on Sunday that 21 bodies were brought to the Upper and Lower Dir districts in Khyber-Pakhtunkhwa (K-P) for burial. "I myself attended the funeral prayer of four fighters, villagers told me they were mujahideen," said Alamzeb Khan, a district official in Lower Dir.
Khan said the coffins were wrapped in the flag of Al Badr, a local militant group linked to the Taliban, and guests at the funeral shouted extremist slogans against US troops in Afghanistan.
The bodies were badly mutilated, and one villager who attended the funeral said the names of the fighters had been written on the wooden coffins for identification. "I fear that the number of fighters killed in the drone strike was high and we may receive more dead bodies," the security official told AFP.
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Khost provincial governor Hukum Khan Habibi said the strike was staged on Wednesday. "In this incident, more than 50 Pakistani fighters were killed."
Faizullah Ghairat, Khost provincial police chief, confirmed the attack and said it was carried out by the US.
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