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De Niro and Scorsese have earlier worked together on 1973 crime thriller Mean Streets and have since collaborated on classics like Taxi Driver, Goodfellas and Raging Bull, reports Digital Spy website.
"We are doing it... We should be doing it sometime next year. We're slowly, slowly getting it in place," De Niro confirmed.
Last month, the 72-year-old actor also spoke about the project while appearing on The Tonight Show with Jimmy Fallon, revealing that Al Pacino and Joe Pesci are also on board for the film.
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Based on the book by Charles Brandt, the film has been in development since at least 2008.
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