The attack came after the Kurdistan Workers Party (PKK) rebel group threatened to no longer observe a truce, following Turkish air strikes on its positions in northern Iraq.
The car bomb went off as the soldiers were travelling on a road in the Lice district of the Diyarbakir province late Saturday, the statement from the Diyarbakir governor's office said.
Read: Air Force: Pakistan, Turkey sign MoU for training pilots
"Two of our personnel were killed in the heinous attack, four were wounded," said the statement, adding that large-scale operations have been launched to find the perpetrators.
The PKK had on Saturday said that the conditions were no longer in place to observe a fragile ceasefire that has largely held since 2013, following the heaviest Turkish air strikes on its positions in northern Iraq since 2011.
The PKK has for decades waged a deadly insurgency in the southeast of Turkey for self-rule that has claimed tens of thousands of lives. A peace process that began in 2013 has so far failed to yield a final deal.
COMMENTS
Comments are moderated and generally will be posted if they are on-topic and not abusive.
For more information, please see our Comments FAQ