According to Express News, the CIA-operated drones first fired at least eight missiles at a compound in Haiderkhel area of Miranshah killing five people. Four people were also injured in the attack.
Locals are sifting through the rubble to recover the bodies of the dead and rescue the injured.
In a second attack in as many hours, drone attacks killed at least three people.
On Saturday, US drones had fired a volley of missiles at militant hideouts in northwest Pakistan on Sunday, killing at least 12 Taliban fighters near the Afghan border, security officials said.
The missile attack took place in Babar Ghar village in South Waziristan, a tribal district bordering Afghanistan which is a stronghold of Taliban and al Qaeda-linked militants.
Earlier in January, a drone strike had reportedly killed militant commander Mullah Nazir.
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