Rose Byrne jokes she finds calm and joy with “drugs and alcohol”

Rose Byrne cracked up listeners when she joked that she finds calm and joy through “drugs and alcohol” when stressed

Actress Rose Byrne had everyone laughing after she offered a hilariously blunt answer about how she copes when overwhelmed, joking that she finds “calm and joy” in drugs and alcohol. The moment quickly became a memorable highlight of the conversation as Byrne delivered the line with her signature dry humour, prompting laughter from those around her.

Known for her roles in comedies like Neighbors and Platonic as well as her dramatic work, Byrne is no stranger to using humour to connect with audiences. In this case, when asked about what helps her find peace amid stress, she leaned into a playful, self-aware comment that clearly wasn’t meant to be taken literally, but instead showcased her ability to riff and keep things light, even when discussing tricky topics.

Fans and onlookers reacted with a mix of amusement and relatability, with many noting that Byrne shouted out the unfiltered thought many have but seldom say out loud. Some joked that her publicist must have done a double-take, while others praised her for appearing authentic and unfazed by PR polish.

The moment also sparked broader online chatter, with people playfully comparing Byrne’s quip to other stars’ candid comments about dealing with pressure, stress and burnout. While drugs and alcohol are obviously not serious wellness recommendations, Byrne’s remark struck a chord because it leaned into humorous honesty, something fans have come to appreciate from her.

It’s worth noting that Byrne has previously shared thoughtful views about wellness and work-life balance in other interviews, showing that she can balance humour with more grounded perspectives on life when the moment calls for it.