Although relations between the neighbours have been strained by accusations over cross-border attacks in recent weeks, Pakistani Prime Minister Yousuf Raza Gilani telephoned Karzai to express his condolences.
Gilani's office said he expressed "shock and grief" over Ahmed Wali Karzai's assassination.
The younger Karzai, who was long accused of involvement in corruption and Afghanistan's drugs trade, was a key ally of the president and US-led Nato forces in the south of the country, the headquarters of a Taliban insurgency.
Pakistan was a key ally of the Afghan Taliban regime until siding with the US-led invasion of Afghanistan that followed the September 11, 2001 attacks and ultimately implanted Karzai in power.
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hmmm they are in action ...they have taken outfirst out of three ....they want their stolen money back....