In this file photo taken on May 23, 2008 The Dalai Lama addresses journalists at his hotel in London. PHOTO: AFP
There he would form a government-in-exile and demand autonomy for Tibet, going on to earn international renown and respect while remaining a bête noire for China.
Here is an account of his dramatic escape.
Buddhist Tibet, a vast Himalayan area of plateaus and mountains, declared independence from China in the early 20th century.
But China took back control in 1951, having sent in thousands of troops.
Lhamo Dhondup, chosen at the age of two in 1937 as the 14th incarnation of Tibetan Buddhism's supreme religious leader under the name Tenzin Gyatso, was enthroned as head of state after the Chinese invasion.
In this file photo taken on May 22, 1959 Picture taken on May 22, 1959 of the Dalai Lama in Birla House Park, Mussoorie's residence (India) where he was invited by the Indian government with his family, members of his court and Tibetan dignitaries, following his flight from Tibet because of the colonialist and repressive policies of China against the Tibetan autonomists. PHOTO: AFPHis co-existence with the Beijing authorities was tense and when the Chinese authorities summoned him to an event without his bodyguards on March 10, Tibetans feared a trap that could endanger their leader.
Thousands assembled at his summer palace to prevent him from leaving; thousands more demonstrated in Lhasa to demand the Chinese depart, the Dalai Lama would later say.
Beijing poured more troops into Tibet: as tensions mounted, they opened fire on March 17, targeting and eventually razing the Dalai Lama's palace.
The revolt was suppressed by March 21, ending in a bloodbath. The government in-exile later claimed the Chinese army killed tens of thousands.
The outside world was largely unaware of the turmoil engulfing isolated and remote Tibet. Only neighbouring India had diplomatic representation there and rare reports of the unrest trickled out via its media.
On March 22 AFP reported from India that there was concern over the fate of the Dalai Lama, then aged 23, who seemed to have disappeared.
"According to some rumours, the young man could be in his Lhasa palace or under Chinese military guard," the report said, citing India's The Statesman newspaper.
It later emerged that he had been able to slip past Chinese troops massed around his palace on March 17, another AFP story said.
In this file photo taken on October 19, 2011 the Dalai Lama prays during a day-long fast and prayer service in honour of Tibetans who set themselves on fire to protest the Chinese rule in Tibet, at Tsuglagkhang Temple in McLeod Ganj. PHOTO: AFPHe left the palace dressed as a soldier and met up with a group of Tibetan resistance fighters 60 kilometres (37 miles) out of Lhasa, AFP reported, again citing The Statesman.
His entourage included his mother, sister, younger brother and several top officials.
They travelled for two days and two nights without stopping, on foot and on horseback, AFP later cited a Tibetan official as saying.
A month's supplies were carried by mules. To cross the major 457-metre-wide (1,500-foot) Brahmaputra River, they used a single boat made of yak skin, the official said.
The group then continued on foot, walking only at night through the harsh Himalayan terrain.
They had a head start on Chinese troops who had not realised the Dalai Lama had disappeared until two days later, only then sending out a ground and air dragnet, and combing monasteries where he could be hiding.
It was "one of the most fantastic escapes in history", an AFP story said.
On March 31 the Dalai Lama walked across the border into the Indian state of Assam.
"The Dalai Lama entered India on March 31 in the evening," Prime Minister Jawaharlal Nehru announced on April 3, AFP sending out the information in a top priority flash.
In mid-April an official statement provided details of his escape. "It is thanks to the affectionate support and the loyalty of his people that the Dalai Lama was able to make his way, by an extremely difficult route," it said.
It denied a Chinese claim that he had been forced into exile.
"The Dalai Lama wishes to categorically state that he left Lhasa and Tibet and came to India of his own free will and not by force", it said.
In this file photo taken on December 10, 1989 Tibetan spiritual leader the Dalai Lama (L) receives the 1989 Nobel Peace Prize from Egil Aarvik, chairman of the Norwegian Nobel Committee on December 10, 1989 at Oslo University. PHOTO: AFPIndia granted the Tibet leader asylum on April 3 and permission to establish a government-in-exile in the northern hill station of Dharamsala, already a sanctuary for thousands of Tibetan exiles fleeing Chinese repression.
From there he launched a campaign to reclaim Tibet, gradually easing this into an appeal for greater autonomy.
Talks between the two sides failed, China adamantly rejecting any suggestion of Tibetan autonomy and blacklisting the Dalai Lama a dangerous "separatist".
Beijing continues to be accused of political and religious repression in the region, but insists Tibetans enjoy extensive freedoms and that it has brought economic growth.
More than 150 Tibetans have set themselves on fire since 2009 in protest against Beijing's presence in Tibet, most of them dying.
The Dalai Lama, who gave up his political role in 2011 but remains based in Dharamsala, has gained worldwide respect for his pacifist approach, winning the Nobel Peace Prize in 1989.
COMMENTS
Comments are moderated and generally will be posted if they are on-topic and not abusive.
For more information, please see our Comments FAQ