"As of 27 January 2019, 17 of the 19 national central banks in the euro area will no longer issue 500-euro banknotes," the European Central Bank (ECB) said on its website.
However, Austria and Germany will both continue printing the banknotes until April 26 "in order to ensure a smooth transition and for logistical reasons," the ECB said.
The 500-euro notes in circulation remain legal tender and can be used to make payments.
The ECB announced in May 2016 that it would halt issuing new 500-euro notes, saying at the time that it expected to do so around the end of 2018, due to "concerns that this banknote could facilitate illicit activities".
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The largest denomination banknote in the single currency area is one of the world's most valuable bills, alongside the 1,000 Swiss franc ($1,017, 888 euros) note.
Because of its high value and portability, experts believe the 500-euro note had become prized by criminals for money laundering and even terrorist financing, earning the nickname "Bin Laden" in some circles.
According to ECB statistics, 500-euro bills account for just 2.4% of the total number of banknotes in circulation, but a little over 20% of the total value. At the end of November, there were 521 million of the banknotes in circulation.
The 500-euro banknotes were actually last printed in 2014, with demand satisfied since from stocks.
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