One security official said the victims had gathered for Friday prayers at the mosque in the Ismail Khel district of Khost province.
Prominent Afghan militia commander among four killed in suicide attack
All those killed in the suicide attack were working for the Afghan security forces, said Captain Abdullah, a military spokesperson in Khost, who goes by only one name.
The Taliban, who are waging a war to oust the Western-backed Afghan government and expel foreign forces from Afghanistan, have launched a series of high-profile attacks against Afghan security forces in recent weeks.
Hundreds of Afghan security guards have been killed, their checkpoints destroyed and weapons seized by the militant fighters.
US 'war on terror' has killed 500,000 people in Pak, Afghanistan and Iraq: study
Friday’s attack came three days after a suicide bomber detonated his explosives at a gathering of religious scholars in Kabul, the capital.
Officials said 55 scholars marking the birthday of the Prophet Mohammad (PBUH) were killed and more than 90 injured in the blast in a banquet hall.
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