The contract to build the plant in Dabaa on the Mediterranean coast was signed during a live ceremony shown on state television and attended by the Russian leader and Egyptian President Abdel Fattah al-Sisi.
Russian military working on deal to use Egyptian air bases
The contract was signed by the head of Russian state nuclear company Rosatom, Alexei Likhachev, and Egypt's electricity and renewable energy minister, Mohamed Shaker.
Egyptian media reports put the cost of the plant at around $30 billion.
The two countries signed two agreements in November 2015 for Russia to finance and build the power plant, with four 1,200 megawatt reactors, in Dabaa.
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