The head of Edhi Foundation breathed his last at the Sindh Institute of Urology and Transplantation (SIUT) on Friday after kidney failure.
The philanthropist was brought to the SIUT after he had trouble in breathing and was subsequently put on ventilator.
Social media quickly lit up in honour of the man whose work uplifting the nation's destitute and orphans cemented his place in the hearts of Pakistan's masses.
Abdul Sattar Edhi passes away in Karachi
"He was a real gem and asset for Pakistan. We have lost a great servant of humanity."
Others lauded him as "the greatest Pakistani", calling his death a "national tragedy".
Here are some of the reactions on Twitter following the announcement of the philanthropist's death:
Pakistan mourns one of its greatest sons but the nation will always remember Edhi for his outstanding services to humanity
— Maleeha Lodhi (@LodhiMaleeha) July 8, 2016
Malala on the death of Abdul Sattar Edhi: "We should learn from him that it is our duty to help those most in need." pic.twitter.com/34jtlr5R3R
— Malala Fund (@MalalaFund) July 8, 2016
Thank you Edhi Sahab for standing up for humanity and devoting your entire life for the cause. #Heroesneverdie pic.twitter.com/8EZBmzshae
— Sana Mir ثناء میر (@mir_sana05) July 8, 2016
Truly saddened to hear of Edhi Sahab's passing. He was a noble soul & a great Pakistani. He gave the first big donation to SKMT 26 years ago
— Imran Khan (@ImranKhanPTI) July 8, 2016
With legendary Edhi sahib passing away not only Pakistan but the world will mourn the loss of a great human being.May he rest in peace-Ameen
— Gen(R) Asim Saleem Bajwa (@AsimBajwaISPR) July 8, 2016
Edhi RIP end of a great innings. In pursuit of ppls welfare he hit politics for 6, yorked colour & religion,ran out terrorism by direct hit
— Ramiz Raja (@iramizraja) July 8, 2016
If ever anyone in recent few decades deserved a state funeral in Pakistan, it has to be EDHI sahb. #statefuneral for EDHI sahib must happen.
— Fakhr-e-Alam S.I & S.E (@falamb3) July 8, 2016
Pakistan has been orphaned tonight
— Talat Aslam (@titojourno) July 8, 2016
RIP Abdus Sattar Edhi
Pakistan's finest son passes away. Rest in peace Edhi sb
— Arooj ZAHRA (@arooojzahra) July 8, 2016
This world is now a poor place without Edhi Saheb. Dear Man with the heart of Gold, May you rest in eternal peace,Innalilaah!
— Maria Memon (@Maria_Memon) July 8, 2016
My heart and sympathies go out to the family of #Edhi sahib. I pray to Allah Almighty to rest his soul in eternal peace.
— Dr Tahir-ul-Qadri (@TahirulQadri) July 8, 2016
Forgive me but I don't even know how to mourn such a big loss. #Edhi
— Farrukh K. Pitafi (@FarrukhKPitafi) July 8, 2016
Devastated, icon of humanity #EdhiSahab passed away..
— Dr. Sharmila sahibah faruqui (Phd) s.i (@sharmilafaruqi) July 8, 2016
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