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The bell, whose chimes feature on British radio broadcasts, will be silenced as part of the £29 million (37 million euros, $42 million) repairs.
The work will repair the clock faces and mechanism, cracks in the tower's masonry and corrosion in the roof, as well as restoring the edging around the clock faces to their original 19th-century colour.
A lift will also be installed as an alternative to the steps up the tower and the lights illuminating the clock will be replaced by low-energy LEDs.
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"The clock mechanism will need to be stopped for several months in order to carry out essential maintenance," a House of Commons spokeswoman said.
"During this period there will be no chimes," she said, adding that "striking and tolling" of the bell would continue for marking important occasions.
"Big Ben" is the name of the bell, while the 315-foot (96-metre) tower holding it is the Elizabeth Tower.
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It was designed in neo-Gothic style by parliament architect Augustus Pugin and was completed in 1856.
"In order to keep the clock ticking, we must now take the time to thoroughly inspect and restore it," said Steve Jaggs, whose title is "Keeper of the Clock".
"The project will enable us to give one of Britain's most famous landmarks the TLC (tender loving care) it so desperately needs and deserves," he said.
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