"A vote to leave Europe represents a risky bet on the country's economic future," the former US Treasury secretaries said in an open letter to The Times newspaper.
Brexit could shrink UK economy by six percent: Treasury
The letter was signed by Timothy Geithner, Henry Paulson, John Snow, Paul O'Neill, Lawrence Summers, Robert Rubin, Michael Blumenthal and George Shultz.
Their warning comes before a visit by US President Barack Obama to visit Britain.
"Brexit could call into question London's role as a global financial centre. For many financial institutions, London has served as the financial springboard into Europe," the former Treasury secretaries said. "A UK turned inward and less engaged in Europe is less able to lead on the critical challenges Europe faces."
EU citizens fear Brexit more than the Brits: survey
A Brexit would disrupt trade and attempts to renegotiate agreements would be difficult, they said.
"The uncertainty surrounding Brexit already appears to be acting as a drag on investment and market sentiment, and a vote to leave could introduce an extended period of uncertainty that could hinder growth even further," they said.
"The better alternative seems to us to work for progress within the confines of EU membership, without incurring the significant economic risk of Brexit: a smaller, slower-growing British economy for years to come," they said.
COMMENTS (1)
Comments are moderated and generally will be posted if they are on-topic and not abusive.
For more information, please see our Comments FAQ