According to various sources, the couple, who have two daughters -- Olive and Frankie -- have separated and plan to divorce soon.
"They’ve been having some difficulties, but they remain close for the sake of their kids," Page Six quoted a source as saying.
Arbaaz Khan and Malaika Arora set for divorce
Another source added: "Drew had a very rebellious and wild childhood, with no family around her, and while she is a very different person now, and a great mother, some of that can stay with you."
It’s the third failed union for Barrymore.
Her first marriage, at age 19, was to bartender Jeremy Thomas in 1994, and lasted less than two months. Her second, in 2001, was to comedian Tom Green, her co-star in Charlie’s Angels, and lasted five months.
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