The immediate cause of the collapse was unknown. The buildings, at least one of which was five storeys tall, were in a street off of Istiklal Avenue, in a district of old buildings and shops popular with tourists and locals.
No one was believed to have been killed or injured, Istanbul Governor Vasip Sahin told CNN Turk.
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The mayor of the local Beyoglu district said one of the shops, a meatball restaurant, had been closed for construction and that the building work may have triggered the collapse.
A police officer at the scene told Reuters there were reports that one of the buildings shook before it started to collapse, giving those inside a chance to run outside.
Waste removal workers were going through the debris and the area was cordoned off.
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