Inter Services Public Relations (ISPR) confirmed the airstrike in the agency but did not immediately confirm human and logistic losses in the incident.
However, civil officers in the political administration said 38 militants were killed in the strike that targeted hideouts in Meezar and Sherani areas just on the Afghanistan border.
Precision bombing: Air strikes kill 23 militants in Tirah, Shawal valleys
Those killed include 15 militants of Uzbek origin associated with Islamic Movement of Uzbekistan, the officials added.
Further, five dens and three explosive-laden vehicles were also destroyed in the airstrike, the officials maintained.
Earlier on December 18, jets carried out airstrikes on terrorist hideouts in the tribal belt near the border with Afghanistan, killing at least 23 militants.
Airstrikes kill 17 militants in Khyber Agency
According to official figures, over 3,400 militants have been killed since the operation was launched half-way through 2014.
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