WWL TV said the shooting occurred around 7 pm local time while about 500 people were at Bunny Friend playground in the city's Upper Ninth Ward for the making of a music video.
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Witnesses told WWL at least two gunmen were shooting into the crowd. The Times-Picayune newspaper quoted witnesses as saying they saw several people lying on the sidewalk after the shooting.
Several ambulances were seen leaving the scene and 10 of the victims were taken to University Medical Center in New Orleans, WWL said.
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The Times-Picayune said New Orleans Mayor Mitch Landrieu had arrived at the scene of the shooting.
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