The 67-year-old Bollywood star said the condition was caused through a blood transfusion following a near-fatal accident while shooting for a film in 1982.
"I was therefore technically, or shall we say in medical terminology, a patient by default. A patient that had developed cirrhosis of the liver -- a condition that is normally associated with that of an alcoholic," Bachchan wrote on his blog on Friday.
Cirrhosis impairs the liver's ability to control infections and process nutrients, hormones and drugs. It is also caused, as in Bachchan's case, by the hepatitis virus.
The damage to the liver was discovered eight years ago, he said, speaking about his ailment for the first time. The latest revelations were prompted by a recent visit to the doctor following an abnormal blood test.
Bachchan's post drew concerned reactions from hundreds of readers and fans, but the actor responded that the condition was just "5 per cent" of what ails him.
It "is a saga that never seems to end, for, what is more in store for me I cannot comprehend," he wrote on Saturday.
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