The Nato force made no immediate comment after the attack, which came as foreign troops rapidly wind down combat operations at the end of a 13-year war against Taliban insurgents.
"At around 11:30am, a convoy of foreign forces was targeted by a suicide bomber in police district 6, killing four civilians and wounding seven," interior ministry spokesperson Sediq Sediqqi said on his Twitter account.
حوالی 11:30 پیش از چاشت امروز در ساحه حوزه ششم کابل کاروان نیروهای خارجی هدف یک حمله انتحاری قرار گرفت 4 ملکی شهید 7 ملکی مجروح گردیده
— Sediq Sediqqi 🇦🇫 (@SediqSediqqi) August 10, 2014
A spokesperson for the Taliban said the insurgents claimed responsibility for the attack.
Ahmad Shah, a shopkeeper at the scene, told AFP: "I saw several people covered in blood around the area. The blast was huge, our windows are shattered.
"Several vehicles were damaged."
US-led foreign troop numbers in Afghanistan have declined from a peak of 150,000 in 2012 to just 44,300 now.
All Nato combat soldiers will depart by the end of the year, though a follow-up support mission of about 10,000 troops is planned if the next president signs security deals with the US and Nato.
Afghanistan's two rival presidential candidates signed a deal Friday to form a national unity government, opening an apparent way forward in a dispute over the election that threatens to revive ethnic conflict.
Ashraf Ghani and Abdullah Abdullah vowed to work together - whoever becomes president - after an ongoing audit of all eight million votes finally declares the winner of the June 14 election.
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R.I.P the innocent people who died.