A file photo of a different train. PHOTO: MOHAMMAD AZEEM/EXPRESS
The train - travelling from Lahore to Karachi - derailed when the driver hit the brakes suddenly after he felt something had collided with the locomotive.
Rescue workers arrived at the scene and shifted injured to a local hospital.
Railway officials said the track will be reopened soon after the maintenance work is completed.
In February, a blast had derailed ten wagons of the Night Coach Express near Dhabeji area.
A six-year-old girl was killed and at least 27 others were injured in the incident.
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