The trucks came under fire in Jamrud area of Khyber agency in FATA as they crossed into Pakistan from Afghanistan.
Pakistan is a key transit route for the NATO mission in landlocked Afghanistan.
"The two trailers were on their way to Karachi when gunmen attacked them at different locations in Jamrud and opened fire on them, wounding their drivers," a local intelligence official told AFP.
A senior local administration official Jehangir Azam Wazir confirmed the incident and said the attackers had fled.
No group claimed responsibility for the attack, however, the Taliban have in the past said they carried out such attacks to disrupt supplies for the US-led international troops fighting in Afghanistan.
Taliban and al Qaeda-linked militants frequently launch attacks across northwestern Pakistan and the lawless tribal belt, which Washington has branded the most dangerous place in the world.
From November 2011 to July 2012, Pakistan shut its Afghan border to overland NATO traffic after botched US air raids that killed 24 Pakistani troops.
Correction: An earlier version of this article incorrectly noted in the headline that the drivers had been killed. The error is regretted.
COMMENTS (3)
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Need accompaniment of drones.
Its common sense that those who threaten to disrupt supply routes have done it. State's responsiblity is to charge them and punish them.
Good job comrades... Want to see more crackers.. Make the end of 2013 rememberable...