"A US drone fired three missiles. The target was a vehicle carrying militants. Four militants were killed," a senior security official in Peshawar told AFP.
An intelligence official in Miranshah also confirmed the attack and toll.
Sixteen US drone attacks have been carried in just 22 days in North Waziristan.
The US missile strikes have killed about 100 people since September 3, while over 1,100 people have been killed in more than 130 drone strikes in Pakistan since August 2008, including a number of senior militants.
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