Rescue teams rushed to the scene after the plane smashed into the ground inside the boundaries of Bagram airfield, a key transport hub for US-led military operations in Afghanistan.
"All seven of the crew on board died in the accident," a spokesperson for the Nato military coalition told AFP.
The spokesperson added that there was no reported insurgent activity in the area at the time.
He declined to discuss the type of plane that was involved in the accident or the cargo company that was operating the flight out of Bagram airbase, 50 kilometres (30 miles) north of Kabul.
Aircraft crashes are fairly frequent in Afghanistan, where the 100,000-strong international military mission relies heavily on air transport as it battles the Taliban insurgency across the country.
A Nato plane crashed in the south on Saturday, killing four US service members, in another incident that the coalition said was not due to insurgent fire.
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It was a 747-400BCF operated by National, an American charter co. The airplane went into a very steep climb (probably due to the load shifting internally), stalled as a result (not enough speed); almost recovered from stall (it was almost horizontal at impact) and finally crashed as it did not have enough altitude for recovery.
.@Stranger - do see the video on Liveleak before making such innane 'conspiracy' comments!
Looks like great pain is taken to make the public believe that its an accident .