According to the police, a mobile was transporting prisoners back to Mardan from Nowshera after presenting them in court for a case hearing when the blast occurred.
According to initial reports, the prisoners were allegedly targeted. None of the prisoners were harmed in the blast and were being transported to a jail in Mardan.
The injured police personnel have been shifted to the district hospital.
Police have cordoned off the area and are investigating the incident.
The situation in Khyber-Pakhtunkhwa has been volatile recently with several blasts taking place in the province, including an attack on the police in Nowshera in June, which injured six personnel.
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RIP may God Save pukhtoons land from evils