The men were detained "on charges of spying for neighbouring regions" and "the arrests were made with concrete evidence", the agency's spokesman, Lutfullah Mashal, told AFP, speaking in English.
The spokesman refused to provide details but a senior intelligence official speaking to AFP under condition of anonymity said the men worked for Iran and Pakistan - both accused of interference in the troubled nation.
"One of them is a senior diplomat at the foreign ministry, he's the deputy head of the Asia desk. The others are government employees in the provinces of Nangarhar (in the east) and Herat (in the west)," the official said.
The arrests were made a month ago, he said.
The official said the senior diplomat and two of the three other men were providing intelligence for the Inter-Services Intelligence agency (ISI), which Afghans accuse of secretly helping Taliban insurgents in Afghanistan.
The foreign ministry was not immediately reachable for comment.
The Taliban, who were in power from 1996 until 2001 when they were ousted in a US-led invasion, are waging an insurgency to topple President Hamid Karzai's Western-backed government.
The fourth person was arrested in Herat, Afghanistan's western trading hub on the border with Iran and Turkmenistan.
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Afghan intelligence cannot stop it's own officers from shooting NATO troops.
@Cautious: Speculation at best buddy. Never read/heard of any Afghan intelligence personnel pointing to any specific location. Mind linking me to such an article?
@Pakistan politics: Then why not show good intentions by having your ISI inform them of what is going on? They might actually look useful.
@Pakistan politics
Perhaps - but they were correct when they told Musharraf that OBL was hiding in Pakistan close to Abbottabad so maybe they are smarter than you think.
Pakistan Politics : And how would you know that genius ? with limited resources they have they are still considered one of the most competent security apparatus of the Afghan security forces.
Vienna,February 27,2012 It looks Afghan officials are vigilant. They should be aggressive and catch Mullah Omer in the first place. Taravadu Taranga Trust for Media Monitoring TTTMM India --Kulamarva Balakrishna