Amy Schumer reveals positive results from Mounjaro weight loss journey after Wegovy side effects, praises hormone therapy

Amy Schumer shares success with Mounjaro and hormone treatment, says perimenopause symptoms have disappeared.

Amy Schumer has opened up about her current health journey, revealing that she’s seeing strong results using the weight loss drug Mounjaro.

In a candid Instagram video filmed from her car, the 43-year-old comedian said she is “having a really good experience” combining Mounjaro with hormone therapy to address symptoms of perimenopause.

The Life & Beth star recalled trying Wegovy three years ago, saying, “I was like puking, I couldn’t handle it. I don’t know if they’ve changed the formula, whatever.” After experiencing negative side effects, Schumer pursued telehealth support and was prescribed estrogen and progesterone. She added Mounjaro to her treatment plan soon after.

 

 

 

 

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“The symptoms of being in perimenopause have disappeared. My hair is fuller, my skin is better, I have more energy. I want to 'get down' more, if you know what I mean,” she said, clarifying with a smile, “I'm talking about sex.”

Schumer told fans she’s aware that Mounjaro is typically prescribed for type 2 diabetes and that insurance rarely covers it for off-label use, joking, “severe obesity, which most of the Internet thinks I have.” Still, she noted the drug has been beneficial for her and wanted to be transparent. “I’m having a really good experience, so I wanted to keep it real with you about that,” she said.

She also credited virtual clinic Midi Health for prescribing the treatment. “I liked it so much, and it was such a good experience that I invested in the company,” she revealed. Other celebrity investors include Connie Britton, Brandi Chastain, Tory Burch, and Sheryl Sandberg’s venture firm.

In her usual comedic tone, Schumer ended the video with a light-hearted promise: “I want to commit to you that I will never get lip fillers, so you can always enjoy that I have no top lip.”