In many cases, the president's opponents have set up barricades that have brought all activity to a standstill.
The crisis shows no signs of abating, with Moise's detractors refusing to come to the negotiating table, and the president far from public view. Here is what you need to know about the crisis, the players and what's at stake for Haiti:
Since he took power in February 2017, Moise has had to face the anger of an opposition movement that refuses to recognise his victory in an election widely seen as dubious.
Haiti gripped by violent protests, rage against president
The first round, initially held in October 2015, was annulled when the candidate who came in second to Moise, Jude Celestin, alleged widespread vote fraud. The run-off was never held.
The election was reorganised in November 2016, and Moise won outright in the first round with more than 55 per cent of the ballots cast, with turnout quite low.
That led some in Haitian politics questioned his legitimacy.
Moise, a businessman with no national profile before 2015, chose a friend, Jack Guy Lafontant, to be his prime minister.
Lafontant, a doctor by training, also had no political experience.
In July 2018, their decision to hike fuel prices sparked three days of riots. Lafontant left office shortly thereafter.
In May this year, Haiti's high court of auditors announced that companies run by Moise before he took office were implicated in an embezzlement scandal to siphon off Venezuelan aid money intended for road repairs -- and the trust gap with the public widened.
In late August, anger mounted due to a fuel shortage, and protests turned violent.
Since then, Moise has been seen infrequently.
Last week, he appeared in public for the first time in more than a month -- he and his wife stopped on the way from their home to the presidential palace to speak with merchants, under the watchful eye of heavily armed police.
He has only spoken to the Haitian people once -- on September 25, in a pre-recorded message broadcast at 2am.
Moise proposed a "historic truce," but his call for dialogue fell flat with his opponents.
Demonstrators, often in the thousands in major cities for big protests, want Moise's immediate resignation.
But the opposition hasn't really offered concrete proposals beyond that for a political transition, especially if there is a power vacuum, and the various parties behind the protests don't agree.
Many protesters have repeatedly called for more transparency in how Haiti has managed aid from Caracas from 2008-2018 within the framework of the Petrocaribe program.
The program -- an initiative of late Venezuelan president Hugo Chavez -- allowed several Latin American and Caribbean countries to access petroleum products at cut-rate prices.
Demonstrators also want anyone suspected in connection with the embezzlement of more than $2 billion from the program, including Moise, to stand trial.
"In Haiti, the richest 20 per cent control more than 60 per cent of the wealth, and the poorest 20 per cent have less than two per cent of the country's wealth," said economist Kesner Pharel.
"This coexistence of villas and slums is an explosive situation, an extremely volatile mix," he told AFP.
"We cannot resolve this crisis with such deep economic inequality."
Haiti has one of the widest rich-poor divides in the world, and its history has been marked by frequent political instability. Moise's tenure is no exception in that respect.
The president has had four prime ministers in two and a half years and, for the last seven months, the government has been run by an administration that tendered its resignation.
Development aid from the International Monetary Fund has not been disbursed, nor has budgetary support from the European Union, Pharel notes.
Haiti police fire rubber pellets at mourners as protests resume
"The international community has demanded that a government be installed and a budget be voted on by lawmakers, but that hasn't happened," he said.
Without that money, Haiti cannot meet the basic needs of its nearly 11 million people, three-fifths of whom lives below the poverty line of $2 a day.
With livelihoods not improving and corruption scandals swirling, a large part of the population has abandoned its faith in politics: only 21 per cent of registered voters cast ballots in 2016.
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