Santillan passed away at a Buenos Aires hospital where he was being treated for injuries suffered in his Saturday fight against Uruguayan Eduardo Abreu, the World Boxing Council (WBC) said on its website.
Russian boxer Maxim Dadashev dies after fight
An ESPN report cited a doctor from the hospital where Santillan was treated said the boxer underwent surgery for a clot in his brain and twice went into cardio respiratory failure before he died of cardiac arrest.
According to fight reports, Santillan's nose began to bleed in the fourth round of the draw against Abreu and he then collapsed in the ring as the result was announced.
Santillan's death comes two days after Russian Maxim Dadashev died at 28 after suffering brain injuries during a fight last Friday in Maryland.
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