At a time of increasing international discord, the leaders will seek to show that transatlantic harmony remains intact as they meet for a second day to salute the heroism of the soldiers who surged onto the Normandy sands on June 6, 1944.
On an occasion that will mix high politics with poignant historical remembrance, Macron will first meet British Prime Minister Theresa May to launch the construction of a British memorial at Ver-sur-Mer.
Macron and Trump will then hold private talks followed by a working lunch after a ceremony at the US military cemetery at Colleville-sur-Mer.
The site overlooking Omaha Beach holds 9,400 graves - just 40 percent of the American forces killed during the weeks of fighting that followed the D-Day landings.
Both leaders will give speeches, while the French president will also bestow the Legion d'Honneur, France's highest honour, on five American veterans.
D-Day is seen by many as one of the great symbols of transatlantic cooperation, as young American servicemen sacrificed their lives in the struggle to end the Third Reich's grip on Europe.
Tens of thousands of French and foreign visitors have converged on the Normandy coast for this year's commemorations to honour the dwindling number of firsthand witnesses to the fighting.
But the Atlantic alliance has been tested by Trump's prickly relations with Europe, as the two sides feud on issues ranging from Iran and Russia to global trade and climate change.
Canadian Prime Minister Justin Trudeau will attend a ceremony at Juno Beach, where Canadian forces were in charge of the assault.
Trump arrives in France from a three-day state visit to Britain, where he attended a ceremony in Portsmouth to mark D-Day alongside Queen Elizabeth II and over a dozen other world leaders.
In a joint proclamation, the 16 nations present at Portsmouth affirmed their shared responsibility to ensure that the horrors of World War II are never repeated.
They reaffirmed their commitment to "shared values" and vowed to work together to defend freedoms "whenever they are threatened".
German Chancellor Angela Merkel, who attended the Portsmouth ceremony, will not be present in Normandy.
President Vladimir Putin, who was invited in 2004 on the 60th anniversary of the invasion, did not receive an invitation to either ceremony, a snub indicative of the West's strained relations with Russia.
Russia's foreign ministry said on Wednesday that the Allied invasion on D-Day did not determine the course of World War II and its importance should not be exaggerated.
Spokesperson Maria Zakharova told journalists that it was the efforts of the Soviet Union, which entered the war in 1941, that secured victory.
On June 6, 1944, now known as the "longest day", 156,000 troops landed on the beaches chosen for the D-Day invasion, most of them American, British and Canadian.
It remains the largest amphibious assault in history, claiming the lives of an estimated 4,400 troops in the first day alone.
"All these guys are my heroes, they're the guys who trained the guys who trained me," Terry Murphy, who spent 21 years as a US Army paratrooper, told AFP on Wednesday at a ceremony in Sannerville to honour Britain's D-Day paratroopers.
"They're really the greatest generation," he said.
Every major D-Day anniversary sees fewer and fewer surviving veterans.
But at the ceremony in Portsmouth, the British Queen said her wartime generation had proved "resilient", noting that some had thought the 60th-anniversary ceremony might be their last.
COMMENTS
Comments are moderated and generally will be posted if they are on-topic and not abusive.
For more information, please see our Comments FAQ