The four girls and two boys were delivered by caesarean section at the 29th week of pregnancy.
"The mother, who is just under 30 years old, and the babies are doing well," a hospital spokesperson said.
According to doctors in the southern Polish city of Krakow, the birth of sextuplets, an extremely rare event, happens once in every 4.7 billion deliveries.
Polish President Andrzej Duda congratulated the parents.
"This is the first case of its kind in Poland," he said on Twitter.
Niesamowita wiadomość! W Krakowie urodziły się dziś 6-raczki. To pierwszy taki przypadek w Polsce. Mama i Dzieci (4 dziewczynki i 2 chłopców) czują się dobrze (jak na tę wyjątkową sytuację). Gratulacje i podziękowania dla Rodzicow i Personelu Medycznego! https://t.co/UoEx57e4YK
— Andrzej Duda (@AndrzejDuda) May 20, 2019
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