The US tech giant said profit jumped 63 per cent from a year ago to $3.0 billion in the fourth quarter as revenues increased 20 per cent to $72.4 billion.
The results reflected growth in Amazon's ever-expanding online retail operations as well as its large cloud computing division known as Amazon Web Services.
Chief executive Jeff Bezos highlighted the role of Amazon's digital assistant, Alexa, as the company moves into infusing artificial intelligence into its smart speakers and other devices in a race for dominance in the "internet of things" market.
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"Alexa was very busy during her holiday season," Bezos said in the earnings release to the stock market.
Bezos pointed to the Amazon-branded Echo speakers that are at the heart of the new strategy.
"Echo Dot was the best-selling item across all products on Amazon globally, and customers purchased millions of more devices from the Echo family compared to last year," he said.
Alexa virtual assistant smarts built into Amazon Echo products spread to scores more products made by partners.
Amazon has been in a battle with Google to have the dominant artificial intelligence aide ready to take spoken commands nearly anywhere.
Amazon has become one of the world's most valuable companies as it moves beyond its traditional retail roots to groceries, streaming media, and a range of other goods and services.
Long known for slim margins, the company has been boosting its profitability in recent years and the latest results showed strong sales for the holiday season.
"Amazon's profits continue to soar on the back of strong online holiday sales, which are simultaneously fueling its white-hot ad business," said eMarketer principal analyst Andrew Lipsman.
He noted that Amazon has been gaining in the digital ad market as a result of its large customer base, developing a new revenue stream and taking away some market share from the leaders, Google and Facebook.
Amazon also has been growing its sales from physical stores including its recently acquired Whole Foods grocery chain.
"On the profit front, Amazon's results are impressive," said Neil Saunders of the research firm GlobalData.
But Saunders said sales growth appears to have slowed as Amazon matured, raising questions about its future path.
"Amazon will now need to work doubly hard to achieve any future sales gains," he said in a research note.
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The end of last year was the biggest holiday shopping season ever for Amazon devices, with customers purchasing millions more of them than they did a year earlier, according to the earnings report.
Amazon launched pop-up stores to customers in six countries across Europe during the holiday season, curating selections of products and hosting events for consumers in Amsterdam, London, Madrid, Milan, Berlin, and Paris.
Amazon shares held in a narrow range as the better-than-expected results were offset in part by a disappointing outlook for sales growth in the current quarter.
The earnings report showed Amazon expenses climbed as the company continued to invest in data centers, distribution networks, artificial intelligence, and original content for its Prime streaming television service that competes with market-leader Netflix.
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