Ventura County Sheriff's Office Sgt Eric Buchow told the CBS affiliate in Los Angeles that there were "multiple fatalities" in the shooting, including a deputy sheriff, and the gunman was dead inside the crowded venue in the upscale residential suburb of Thousand Oaks.
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The venue was hosting an event for college students and possibly several hundred young people were inside, said Captain Garo Kuredjian of the Ventura County Sheriff's office.
He said around 0915 GMT that the shooter was still confined inside the premises, adding he did not know if the shooter had been subdued or shot.
Police who responded to reports of a shooting rushed to the scene and engaged the gunman, said Kuredjian.
The incident happened at the Borderline Bar and Grill in the town of Thousand Oaks, a quiet, upscale residential suburb of Los Angeles.
The Los Angeles Times quoted a law enforcement official as saying at least 30 shots had been fired.
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An unnamed witness told the newspaper that someone ran into the bar around 11:30 pm and started shooting what looked to be a black pistol.
"He shot a lot, at least 30 times. I could still hear gunshots after everyone left," the Times quoted the man as saying.
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