Rani was born on December 8, 1946 as Nasira Sarfraz in Mozang, Lahore.
She gained success in late 1960s when she made a hit pair with famous actor and producer Waheed Murad, with her first movie being Mehboob.
Some of her more notable films are Chann Makhna, Sajjan Pyara, Jind Jan, Duniya Matlib Di, Anjuman, Tehzeeb, Umrao Jan Ada, Naag Muuni, Seeta Mariam Margaret and Ik Gunah Aur Sahi.
She also acted in two TV serials Khowahish and Faraib in the early 90's.
Rani died of cancer on May 27,1993, at the age of 46 in Karachi.
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