Sampaoli has publicly recognised his desire to take the vacant role as Argentina boss to aid the two-time world champion's faltering World Cup qualification campaign.
"There's a clear intention from my country to have me as coach and, since I was young, it's something that has appealed to me," said Sampaoli on Friday.
Despite a disappointing dip in form in recent months, Sevilla have overall had a successful season in finishing fourth under Sampaoli and gave their campaign a final flourish by sweeping aside already relegated Osasuna.
Vitolo tapped home the opener after just 10 minutes when Salvatore Sirigu could only parry Joaquin Correa's shot.
Vazquez then slotted home his first from Sergio Escudero's cross before Steven Jovetic rifled in a third before half-time.
Mariano's teasing cross was blasted home by Vazquez on the hour mark and Vitolo rounded off the scoring with the sort of fine solo run and finish that has seen him become a transfer target for Atletico Madrid.
Sampaoli out to halt Real’s La Liga charge
Earlier, Deportivo la Coruna thrashed Las Palmas 3-0 to finish in 16th ahead of Leganes, who drew 1-1 at home to Alaves.
Sporting Gijon will join Osasuna in the Segunda Division next season and couldn't give their fans a third straight win to cheer in a 2-2 draw with Real Betis.
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