"We had a very, very good meeting" Trump said shortly after the meeting.
"We're going to stop the killing and the death [in Syria]," he added.
Lavrov on Wednesday became the most senior Russian official to meet Trump since he came to office, and the most high-profile Kremlin official to visit the White House in years.
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It is rare for a foreign minister - or any non-head of state representing a foreign country - to be given a meeting in the Oval Office.
"I think that we are going to do very well with respect to Syria, I think things are happening - they are really, really, really positive," Trump said.
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