Madrid host local rivals Atletico Madrid in La Liga on Saturday before travelling to face Bayern Munich in the first leg of their Champions League quarter-final on April 12.
Bizarre Ronaldo statue overshadows airport naming event
Ronaldo is one yellow card away from picking up an automatic suspension and a booking -- a fifth this season -- against Leganes would have seen him miss the derby.
German midfielder Toni Kroos was also left out of Zidane's 19-man squad.
Captain fantastic Ramos leads Real to top of La Liga
However, Keylor Navas, Sergio Ramos, Marcelo, Casemiro and James Rodriguez return after missing Sunday's 3-0 win over Alaves.
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