"An explosive device was detonated on Bagram Airfield resulting in multiple casualties. Response teams at Bagram continue to treat the wounded and investigate the incident," the military coalition said in a statement.
Claiming responsibility for the attack, Taliban spokesperson Zabihullah Mujahid said that it was a suicide attack 'inside' the airbase.
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"We can confirm that there was an explosion at Bagram Airfield this morning just after 5:30 am. There have been casualties," the military coalition said in a brief statement. "Our Force Protection and medical teams are responding to the situation," it added, without offering any other details.
The explosion underscores a worsening security situation nearly two years after NATO formally ended its combat operations in Afghanistan. Bagram Airfield, close to Kabul, has frequently come under attack by Taliban insurgents.
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Last December, a motorcycle-riding Taliban suicide bomber killed six US soldiers near Afghanistan's largest US military base. It was one of the deadliest attacks on foreign troops in the country in 2015.
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