Kevin de Bruyne, who was never appreciated by Mourinho when they were at Chelsea together, proved instrumental in City's magnificent win, scoring the opener and making the second for Kelechi Iheanacho before halftime.
Guardiola, Mourinho ready to resume hostilities in Manchester derby
With his side being outpassed and outclassed in a one-sided first half, Zlatan Ibrahimovic brought United back into the match just before the break after a mistake by City's new goalkeeper Claudio Bravo.
Bravo's error on a hugely unconvincing debut inspired a much more even second half and Ibrahimovic had goal ruled out for offside before man of the match De Bruyne hit the post as City maintained their 100 percent record this season to move three points clear at the top of the table.
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